Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery | Nature Biotechnology
Ig germ line transcription and recombination is dependent on E2A. (A)... | Download Scientific Diagram
Rearrangement of Mouse Immunoglobulin Kappa Deleting Element Recombining Sequence Promotes Immune Tolerance and Lambda B Cell Production: Immunity
Organization of the endogenous kappa light chain locus and reporter... | Download Scientific Diagram
Deletion of the Igκ Light Chain Intronic Enhancer/Matrix Attachment Region Impairs but Does Not Abolish VκJκ Rearrangement - ScienceDirect
IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms | Nature Communications
Deletion of the Igκ Light Chain Intronic Enhancer/Matrix Attachment Region Impairs but Does Not Abolish VκJκ Rearrangement - ScienceDirect
Intra-Vκ Cluster Recombination Shapes the Ig Kappa Locus Repertoire - ScienceDirect
LMP1-augmented kappa intron enhancer activity contributes to upregulation expression of Ig kappa light chain via NF-kappaB and AP-1 pathways in nasopharyngeal carcinoma cells | Molecular Cancer | Full Text
Mapping of human nuclear factor kappa-light-chain enhancer of... | Download Scientific Diagram
Binary outcomes of enhancer activity underlie stable random monoallelic expression | eLife
Cancers | Free Full-Text | Enhancing B-Cell Malignancies—On Repurposing Enhancer Activity towards Cancer
Essential roles of the κ light chain intronic enhancer and 3′ enhancer in κ rearrangement and demethylation | Nature Immunology
Frontiers | Contribution of Immunoglobulin Enhancers to B Cell Nuclear Organization
B cells engineered to express pathogen-specific antibodies protect against infection | Science Immunology
Two Forms of Loops Generate the Chromatin Conformation of the Immunoglobulin Heavy-Chain Gene Locus: Cell
Frontiers | Igh Locus Polymorphism May Dictate Topological Chromatin Conformation and V Gene Usage in the Ig Repertoire
LMP1-augmented kappa intron enhancer activity contributes to upregulation expression of Ig kappa light chain via NF-kappaB and AP-1 pathways in nasopharyngeal carcinoma cells | Molecular Cancer | Full Text
Frontiers | Contribution of Immunoglobulin Enhancers to B Cell Nuclear Organization
Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties | PNAS
OcaB Is Required for Normal Transcription and V(D)J Recombination of a Subset of Immunoglobulin κ Genes: Cell
Enhancer–promoter communication and transcriptional regulation of Igh - ScienceDirect
Immunoglobulin heavy chain locus and B cell development. Schematic of... | Download Scientific Diagram
ETS Protein–Dependent Accessibility Changes at the Immunoglobulin μ Heavy Chain Enhancer: Immunity